Yes – you can initiate actions in bulk by selecting multiple Senders using the associated checkboxes on the left hand side of the Sender list. When you select several Senders, a new menu will appear at the top of the Sender list, with the option to ‘Allow’ (checkmark), ‘Block’ (X), ‘Filter’ (filter icon), or the ellipses where you can update Destination Email addresses or Group settings. Whatever action you take here will apply to all selected Senders.

Note that if you have a Filter already enabled for any selected Sender, you will not see the bulk action Filter button as an option – to enable it, you must remove the Filter on that particular Sender first.